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Deletion of mFICD AMPylase alters cytokine secretion and affects visual short-term learning in vivo

Fic domain-containing AMP transferases (fic AMPylases) are conserved enzymes that catalyze the covalent transfer of AMP to proteins. This posttranslational modification regulates the function of several proteins, including the ER-resident chaperone Grp78/BiP. Here we introduce a mouse FICD (mFICD) A...

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Detalles Bibliográficos
Autores principales: McCaul, Nicholas, Porter, Corey M., Becker, Anouk, Tang, Chih-Hang Anthony, Wijne, Charlotte, Chatterjee, Bhaskar, Bousbaine, Djenet, Bilate, Angelina, Hu, Chih-Chi Andrew, Ploegh, Hidde, Truttmann, Matthias C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8441161/
https://www.ncbi.nlm.nih.gov/pubmed/34419450
http://dx.doi.org/10.1016/j.jbc.2021.100991