Mitochondrial contact site and cristae organizing system (MICOS) machinery supports heme biosynthesis by enabling optimal performance of ferrochelatase

Heme is an essential cofactor required for a plethora of cellular processes in eukaryotes. In metazoans the heme biosynthetic pathway is typically partitioned between the cytosol and mitochondria, with the first and final steps taking place in the mitochondrion. The pathway has been extensively stud...

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Detalles Bibliográficos
Autores principales: Dietz, Jonathan V., Willoughby, Mathilda M., Piel, Robert B., Ross, Teresa A., Bohovych, Iryna, Addis, Hannah G., Fox, Jennifer L., Lanzilotta, William N., Dailey, Harry A., Wohlschlegel, James A., Reddi, Amit R., Medlock, Amy E., Khalimonchuk, Oleh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8441213/
https://www.ncbi.nlm.nih.gov/pubmed/34517185
http://dx.doi.org/10.1016/j.redox.2021.102125

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8441213/
https://www.ncbi.nlm.nih.gov/pubmed/34517185
http://dx.doi.org/10.1016/j.redox.2021.102125

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