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Identification of peroxiredoxin 6 as a direct target of withangulatin A by quantitative chemical proteomics in non-small cell lung cancer

Peroxiredoxin 6 (PRDX6), as a bifunctional enzyme with glutathione peroxidase activity (GPx) and Ca2(+)-independent phospholipase A2 (iPLA2) activity, has a higher expression in various cancer cells, which leads to the increase of antioxidant properties and promotes tumorigenesis. However, only a fe...

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Detalles Bibliográficos
Autores principales: Chen, Chen, Gong, Lijie, Liu, Xiaoqin, Zhu, Tianyu, Zhou, Wuxi, Kong, Lingyi, Luo, Jianguang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8441215/
https://www.ncbi.nlm.nih.gov/pubmed/34517184
http://dx.doi.org/10.1016/j.redox.2021.102130