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Identification of peroxiredoxin 6 as a direct target of withangulatin A by quantitative chemical proteomics in non-small cell lung cancer
Peroxiredoxin 6 (PRDX6), as a bifunctional enzyme with glutathione peroxidase activity (GPx) and Ca2(+)-independent phospholipase A2 (iPLA2) activity, has a higher expression in various cancer cells, which leads to the increase of antioxidant properties and promotes tumorigenesis. However, only a fe...
Autores principales: | Chen, Chen, Gong, Lijie, Liu, Xiaoqin, Zhu, Tianyu, Zhou, Wuxi, Kong, Lingyi, Luo, Jianguang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8441215/ https://www.ncbi.nlm.nih.gov/pubmed/34517184 http://dx.doi.org/10.1016/j.redox.2021.102130 |
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