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Multiple mechanisms for TRAF3-mediated regulation of the T cell costimulatory receptor GITR

Tumor necrosis factor receptor (TNFR)-associated factor 3 (TRAF3) plays context-specific roles in multiple receptor-mediated signaling pathways in different cell types. Mice lacking TRAF3 in T cells display defective T-cell-mediated immune responses to immunization and infection and demonstrate defe...

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Detalles Bibliográficos
Autores principales: Li, Hanzeng, Hostager, Bruce S., Arkee, Tina, Bishop, Gail A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8441216/
https://www.ncbi.nlm.nih.gov/pubmed/34418432
http://dx.doi.org/10.1016/j.jbc.2021.101097