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Development of the Bone Phenotype and microRNA Profile in Adults With Low‐Density Lipoprotein Receptor‐Related Protein 5–High Bone Mass (LRP5‐HBM) Disease

Pathogenic variants in the Wnt‐pathway co‐receptor low‐density lipoprotein (LDL) receptor‐related protein 5 (LRP5) cause high bone mass (LRP5‐HBM) due to insensitivity to the endogenous antagonist of Wnt‐signaling. Although indicating incessant progression of BMD and biomarkers reflecting bone forma...

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Detalles Bibliográficos
Autores principales: Lauterlein, Jens‐Jacob Lindegaard, Gossiel, Fatma, Weigl, Moritz, Eastell, Richard, Hackl, Matthias, Hermann, Pernille, Bollerslev, Jens, Frost, Morten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8441296/
https://www.ncbi.nlm.nih.gov/pubmed/34532618
http://dx.doi.org/10.1002/jbm4.10534