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Altered sperm tsRNAs in aged male contribute to anxiety‐like behavior in offspring

Parental age at first pregnancy is increasing worldwide. The offspring of aged father has been associated with higher risk of several neuropsychiatric disorders, such as schizophrenia and autism, but the underlying mechanism remains elusive. Here we report that advanced paternal age in mice alters t...

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Detalles Bibliográficos
Autores principales: Guo, Yi, Bai, Dandan, Liu, Wenqiang, Liu, Yingdong, Zhang, Yalin, Kou, Xiaochen, Chen, Jiayu, Wang, Hong, Teng, Xiaoming, Zuo, Ji, Gao, Shaorong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8441364/
https://www.ncbi.nlm.nih.gov/pubmed/34448534
http://dx.doi.org/10.1111/acel.13466