PP‐1β and PP‐2Aα modulate cAMP response element‐binding protein (CREB) functions in aging control and stress response through de‐regulation of αB‐crystallin gene and p300‐p53 signaling axis

The function of the transcription factor, cAMP response element‐binding protein (CREB), is activated through S133 phosphorylation by PKA and others. Regarding its inactivation, it is not well defined. cAMP response element‐binding protein plays an essential role in promoting cell proliferation, neur...

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Detalles Bibliográficos
Autores principales: Wang, Ling, Zhang, Lan, Gong, Xiao‐Dong, Fu, Jia‐Ling, Gan, Yu‐Wen, Hou, Min, Nie, Qian, Xiang, Jia‐Wen, Xiao, Yuan, Wang, Yan, Zheng, Shu‐Yu, Yang, Lan, Chen, Huimin, Xiang, Meng‐Qing, Liu, Yizhi, Li, David Wan‐Cheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8441381/
https://www.ncbi.nlm.nih.gov/pubmed/34425033
http://dx.doi.org/10.1111/acel.13458

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8441381/
https://www.ncbi.nlm.nih.gov/pubmed/34425033
http://dx.doi.org/10.1111/acel.13458

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