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The antagonistic pleiotropy of insulin‐like growth factor 1

While insulin‐like growth factor‐1 (IGF‐1) is a well‐established modulator of aging and longevity in model organisms, its role in humans has been controversial. In this study, we used the UK Biobank (n = 440,185) to resolve previous ambiguities in the relationship between serum IGF‐1 levels and clin...

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Detalles Bibliográficos
Autores principales: Zhang, William B., Ye, Kenny, Barzilai, Nir, Milman, Sofiya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8441393/
https://www.ncbi.nlm.nih.gov/pubmed/34363732
http://dx.doi.org/10.1111/acel.13443