Inhibition of TGF‐β Increases Bone Volume and Strength in a Mouse Model of Osteogenesis Imperfecta

Osteogenesis imperfecta (OI), is a genetic disorder of bone fragility caused by mutations in collagen I or proteins involved in collagen processing. Previous studies in mice and human OI bones have shown that excessive activation of TGF‐β signaling plays an important role in dominant and recessive O...

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Detalles Bibliográficos
Autores principales: Greene, Benjamin, Russo, Ryan J, Dwyer, Shannon, Malley, Katie, Roberts, Errin, Serrielo, Joseph, Piepenhagen, Peter, Cummings, Sheila, Ryan, Susan, Zarazinski, Christine, Uppuganti, Sasidhar, Bukanov, Nikolai, Nyman, Jeffry S, Cox, Megan K, Liu, Shiguang, Ibraghimov‐Beskrovnaya, Oxana, Sabbagh, Yves
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8441395/
https://www.ncbi.nlm.nih.gov/pubmed/34532615
http://dx.doi.org/10.1002/jbm4.10530

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8441395/
https://www.ncbi.nlm.nih.gov/pubmed/34532615
http://dx.doi.org/10.1002/jbm4.10530

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