Cargando…

Synaptic dysregulation and hyperexcitability induced by intracellular amyloid beta oligomers

Intracellular amyloid beta oligomer (iAβo) accumulation and neuronal hyperexcitability are two crucial events at early stages of Alzheimer's disease (AD). However, to date, no mechanism linking iAβo with an increase in neuronal excitability has been reported. Here, the effects of human AD brain...

Descripción completa

Detalles Bibliográficos
Autores principales: Fernandez‐Perez, Eduardo J., Muñoz, Braulio, Bascuñan, Denisse A., Peters, Christian, Riffo‐Lepe, Nicolas O., Espinoza, Maria P., Morgan, Peter J., Filippi, Caroline, Bourboulou, Romain, Sengupta, Urmi, Kayed, Rakez, Epsztein, Jérôme, Aguayo, Luis G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8441418/
https://www.ncbi.nlm.nih.gov/pubmed/34409748
http://dx.doi.org/10.1111/acel.13455