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Host autophagy mediates organ wasting and nutrient mobilization for tumor growth

During tumor growth—when nutrient and anabolic demands are high—autophagy supports tumor metabolism and growth through lysosomal organelle turnover and nutrient recycling. Ras‐driven tumors additionally invoke non‐autonomous autophagy in the microenvironment to support tumor growth, in part through...

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Detalles Bibliográficos
Autores principales: Khezri, Rojyar, Holland, Petter, Schoborg, Todd Andrew, Abramovich, Ifat, Takáts, Szabolcs, Dillard, Caroline, Jain, Ashish, O'Farrell, Fergal, Schultz, Sebastian Wolfgang, Hagopian, William M, Quintana, Eduardo Martin, Ng, Rachel, Katheder, Nadja Sandra, Rahman, Mohammed Mahidur, Teles Reis, José Gerardo, Brech, Andreas, Jasper, Heinrich, Rusan, Nasser M, Jahren, Anne Hope, Gottlieb, Eyal, Rusten, Tor Erik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8441431/
https://www.ncbi.nlm.nih.gov/pubmed/34309071
http://dx.doi.org/10.15252/embj.2020107336