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Accurate prediction of B-form/A-form DNA conformation propensity from primary sequence: A machine learning and free energy handshake
DNA carries the genetic code of life, with different conformations associated with different biological functions. Predicting the conformation of DNA from its primary sequence, although desirable, is a challenging problem owing to the polymorphic nature of DNA. We have deployed a host of machine lea...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8441556/ https://www.ncbi.nlm.nih.gov/pubmed/34553171 http://dx.doi.org/10.1016/j.patter.2021.100329 |