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Coarse-grained simulations uncover Gram-negative bacterial defense against polymyxins by the outer membrane
The outer membrane (OM) of Gram-negative bacteria is a formidable barrier against antibiotics. Understanding the structure and function of the OM is essential for the discovery of novel membrane-acting agents against multidrug-resistant Gram-negative pathogens. However, it remains challenging to obt...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Research Network of Computational and Structural Biotechnology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8441625/ https://www.ncbi.nlm.nih.gov/pubmed/34584634 http://dx.doi.org/10.1016/j.csbj.2021.06.051 |