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Dimethyl sulfoxide reduces the stability but enhances catalytic activity of the main SARS‐CoV‐2 protease 3CLpro

Severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) is responsible for coronavirus disease 2019 (COVID‐19), one of the most challenging global pandemics of the modern era. Potential treatment strategies against COVID‐19 are yet to be devised. It is crucial that antivirals that interfere wit...

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Detalles Bibliográficos
Autores principales: Ferreira, Juliana C., Fadl, Samar, Ilter, Metehan, Pekel, Hanife, Rezgui, Rachid, Sensoy, Ozge, Rabeh, Wael M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8441638/
https://www.ncbi.nlm.nih.gov/pubmed/34324734
http://dx.doi.org/10.1096/fj.202100994