Integrative Network-Based Analysis Reveals Gene Networks and Novel Drug Repositioning Candidates for Alzheimer Disease

BACKGROUND AND OBJECTIVES: To integrate genome-wide association study data with tissue-specific gene expression information to identify coexpression networks, biological pathways, and drug repositioning candidates for Alzheimer disease. METHODS: We integrated genome-wide association summary statisti...

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Detalles Bibliográficos
Autores principales: Gerring, Zachary F., Gamazon, Eric R., White, Anthony, Derks, Eske M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8441674/
https://www.ncbi.nlm.nih.gov/pubmed/34532569
http://dx.doi.org/10.1212/NXG.0000000000000622

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8441674/
https://www.ncbi.nlm.nih.gov/pubmed/34532569
http://dx.doi.org/10.1212/NXG.0000000000000622

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