Molecular definition of severe acute respiratory syndrome coronavirus 2 receptor‐binding domain mutations: Receptor affinity versus neutralization of receptor interaction

BACKGROUND: Several new variants of SARS‐CoV‐2 have emerged since fall 2020 which have multiple mutations in the receptor‐binding domain (RBD) of the spike protein. It is unclear which mutations affect receptor affinity versus immune recognition. METHODS: We produced wild type RBD, RBD with single m...

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Detalles Bibliográficos
Autores principales: Vogel, Monique, Augusto, Gilles, Chang, Xinyue, Liu, Xuelan, Speiser, Daniel, Mohsen, Mona O., Bachmann, Martin F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
ORIGINAL ARTICLES
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8441680/
https://www.ncbi.nlm.nih.gov/pubmed/34240429
http://dx.doi.org/10.1111/all.15002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8441680/
https://www.ncbi.nlm.nih.gov/pubmed/34240429
http://dx.doi.org/10.1111/all.15002

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