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Molecular definition of severe acute respiratory syndrome coronavirus 2 receptor‐binding domain mutations: Receptor affinity versus neutralization of receptor interaction
BACKGROUND: Several new variants of SARS‐CoV‐2 have emerged since fall 2020 which have multiple mutations in the receptor‐binding domain (RBD) of the spike protein. It is unclear which mutations affect receptor affinity versus immune recognition. METHODS: We produced wild type RBD, RBD with single m...
Autores principales: | Vogel, Monique, Augusto, Gilles, Chang, Xinyue, Liu, Xuelan, Speiser, Daniel, Mohsen, Mona O., Bachmann, Martin F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8441680/ https://www.ncbi.nlm.nih.gov/pubmed/34240429 http://dx.doi.org/10.1111/all.15002 |
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