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Optimal CD8(+) T‐cell memory formation following subcutaneous cytomegalovirus infection requires virus replication but not early dendritic cell responses

Cytomegalovirus (CMV) induction of large frequencies of highly functional memory T cells has attracted much interest in the utility of CMV‐based vaccine vectors, with exciting preclinical data obtained in models of infectious diseases and cancer. However, pathogenesis of human CMV (HCMV) remains a c...

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Detalles Bibliográficos
Autores principales: Dimonte, Sandra, Gimeno‐Brias, Silvia, Marsden, Morgan, Chapman, Lucy, Sabberwal, Pragati, Clement, Mathew, Humphreys, Ian R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8442243/
https://www.ncbi.nlm.nih.gov/pubmed/34003499
http://dx.doi.org/10.1111/imm.13368