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The 3D nuclear conformation of the major histocompatibility complex changes upon cell activation both in porcine and human macrophages

BACKGROUND: The crucial role of the major histocompatibility complex (MHC) for the immune response to infectious diseases is well-known, but no information is available on the 3D nuclear organization of this gene-dense region in immune cells, whereas nuclear architecture is known to play an essentia...

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Detalles Bibliográficos
Autores principales: Mompart, Florence, Kamgoué, Alain, Lahbib-Mansais, Yvette, Robelin, David, Bonnet, Agnès, Rogel-Gaillard, Claire, Kocanova, Silvia, Yerle-Bouissou, Martine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8442435/
https://www.ncbi.nlm.nih.gov/pubmed/34521351
http://dx.doi.org/10.1186/s12860-021-00384-4