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The 3D nuclear conformation of the major histocompatibility complex changes upon cell activation both in porcine and human macrophages
BACKGROUND: The crucial role of the major histocompatibility complex (MHC) for the immune response to infectious diseases is well-known, but no information is available on the 3D nuclear organization of this gene-dense region in immune cells, whereas nuclear architecture is known to play an essentia...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8442435/ https://www.ncbi.nlm.nih.gov/pubmed/34521351 http://dx.doi.org/10.1186/s12860-021-00384-4 |