Association between circulating alpha-1 antitrypsin polymers and lung and liver disease

BACKGROUND: Alpha-1 antitrypsin deficiency (AATD) is considered one of the most common genetic diseases and is characterised by the misfolding and polymerisation of the alpha-1 antitrypsin (AAT) protein within hepatocytes. The relevance of circulating polymers (CP) of AAT in the pathogenesis of lung...

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Detalles Bibliográficos
Autores principales: Núñez, Alexa, Belmonte, Irene, Miranda, Elena, Barrecheguren, Miriam, Farago, Georgina, Loeb, Eduardo, Pons, Mònica, Rodríguez-Frías, Francisco, Gabriel-Medina, Pablo, Rodríguez, Esther, Genescà, Joan, Miravitlles, Marc, Esquinas, Cristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8442448/
https://www.ncbi.nlm.nih.gov/pubmed/34526035
http://dx.doi.org/10.1186/s12931-021-01842-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8442448/
https://www.ncbi.nlm.nih.gov/pubmed/34526035
http://dx.doi.org/10.1186/s12931-021-01842-5

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