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p53 Activation Effect in the Balance of T Regulatory and Effector Cell Subsets in Patients With Thyroid Cancer and Autoimmunity

Carcinomas evade the host immune system by negatively modulating CD4+ and CD8+ T effector lymphocytes through forkhead box protein 3 (FOXP3) positive T regulatory cells’ increased activity. Furthermore, interaction of the programmed cell death 1 (PD1) molecule and its ligand programmed cell death li...

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Detalles Bibliográficos
Autores principales: Arena, Andrea, Stigliano, Antonio, Belcastro, Eugenia, Giorda, Ezio, Rosado, Maria Manuela, Grossi, Armando, Assenza, Maria Rita, Moretti, Fabiola, Fierabracci, Alessandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8442659/
https://www.ncbi.nlm.nih.gov/pubmed/34539667
http://dx.doi.org/10.3389/fimmu.2021.728381