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p53 Activation Effect in the Balance of T Regulatory and Effector Cell Subsets in Patients With Thyroid Cancer and Autoimmunity
Carcinomas evade the host immune system by negatively modulating CD4+ and CD8+ T effector lymphocytes through forkhead box protein 3 (FOXP3) positive T regulatory cells’ increased activity. Furthermore, interaction of the programmed cell death 1 (PD1) molecule and its ligand programmed cell death li...
Autores principales: | Arena, Andrea, Stigliano, Antonio, Belcastro, Eugenia, Giorda, Ezio, Rosado, Maria Manuela, Grossi, Armando, Assenza, Maria Rita, Moretti, Fabiola, Fierabracci, Alessandra |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8442659/ https://www.ncbi.nlm.nih.gov/pubmed/34539667 http://dx.doi.org/10.3389/fimmu.2021.728381 |
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