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RE-SELEX: restriction enzyme-based evolution of structure-switching aptamer biosensors

Aptamers are widely employed as recognition elements in small molecule biosensors due to their ability to recognize small molecule targets with high affinity and selectivity. Structure-switching aptamers are particularly promising for biosensing applications because target-induced conformational cha...

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Detalles Bibliográficos
Autores principales: Sanford, Aimee A., Rangel, Alexandra E., Feagin, Trevor A., Lowery, Robert G., Argueta-Gonzalez, Hector S., Heemstra, Jennifer M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8442683/
https://www.ncbi.nlm.nih.gov/pubmed/34659704
http://dx.doi.org/10.1039/d1sc02715h