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Coumarin luciferins and mutant luciferases for robust multi-component bioluminescence imaging

Multi-component bioluminescence imaging requires an expanded collection of luciferase–luciferin pairs that emit far-red or near-infrared light. Toward this end, we prepared a new class of luciferins based on a red-shifted coumarin scaffold. These probes (CouLuc-1s) were accessed in a two-step sequen...

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Detalles Bibliográficos
Autores principales: Yao, Zi, Caldwell, Donald R., Love, Anna C., Kolbaba-Kartchner, Bethany, Mills, Jeremy H., Schnermann, Martin J., Prescher, Jennifer A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8442684/
https://www.ncbi.nlm.nih.gov/pubmed/34659703
http://dx.doi.org/10.1039/d1sc03114g