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The WIPI Gene Family and Neurodegenerative Diseases: Insights From Yeast and Dictyostelium Models

WIPIs are a conserved family of proteins with a characteristic 7-bladed β-propeller structure. They play a prominent role in autophagy, but also in other membrane trafficking processes. Mutations in human WIPI4 cause several neurodegenerative diseases. One of them is BPAN, a rare disease characteriz...

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Detalles Bibliográficos
Autores principales: Vincent, Olivier, Antón-Esteban, Laura, Bueno-Arribas, Miranda, Tornero-Écija, Alba, Navas, María-Ángeles, Escalante, Ricardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8442847/
https://www.ncbi.nlm.nih.gov/pubmed/34540850
http://dx.doi.org/10.3389/fcell.2021.737071