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The WIPI Gene Family and Neurodegenerative Diseases: Insights From Yeast and Dictyostelium Models
WIPIs are a conserved family of proteins with a characteristic 7-bladed β-propeller structure. They play a prominent role in autophagy, but also in other membrane trafficking processes. Mutations in human WIPI4 cause several neurodegenerative diseases. One of them is BPAN, a rare disease characteriz...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8442847/ https://www.ncbi.nlm.nih.gov/pubmed/34540850 http://dx.doi.org/10.3389/fcell.2021.737071 |