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De novo design of peptides that coassemble into β sheet–based nanofibrils

Peptides’ hierarchical coassembly into nanostructures enables controllable fabrication of multicomponent biomaterials. In this work, we describe a computational and experimental approach to design pairs of charge-complementary peptides that selectively coassemble into β-sheet nanofibers when mixed t...

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Detalles Bibliográficos
Autores principales: Xiao, Xingqing, Wang, Yiming, Seroski, Dillon T., Wong, Kong M., Liu, Renjie, Paravastu, Anant K., Hudalla, Gregory A., Hall, Carol K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8442925/
https://www.ncbi.nlm.nih.gov/pubmed/34516924
http://dx.doi.org/10.1126/sciadv.abf7668