Cristae-dependent quality control of the mitochondrial genome

Mitochondrial genomes (mtDNA) encode essential subunits of the mitochondrial respiratory chain. Mutations in mtDNA can cause a shortage in cellular energy supply, which can lead to numerous mitochondrial diseases. How cells secure mtDNA integrity over generations has remained unanswered. Here, we sh...

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Detalles Bibliográficos
Autores principales: Jakubke, Christopher, Roussou, Rodaria, Maiser, Andreas, Schug, Christina, Thoma, Felix, Bunk, David, Hörl, David, Leonhardt, Heinrich, Walter, Peter, Klecker, Till, Osman, Christof
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8442932/
https://www.ncbi.nlm.nih.gov/pubmed/34516914
http://dx.doi.org/10.1126/sciadv.abi8886

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8442932/
https://www.ncbi.nlm.nih.gov/pubmed/34516914
http://dx.doi.org/10.1126/sciadv.abi8886

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