The opportunistic intracellular bacterial pathogen Rhodococcus equi elicits type I interferon by engaging cytosolic DNA sensing in macrophages

Rhodococcus equi is a major cause of foal pneumonia and an opportunistic pathogen in immunocompromised humans. While alveolar macrophages constitute the primary replicative niche for R. equi, little is known about how intracellular R. equi is sensed by macrophages. Here, we discovered that in additi...

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Detalles Bibliográficos
Autores principales: Vail, Krystal J., da Silveira, Bibiana Petri, Bell, Samantha L., Cohen, Noah D., Bordin, Angela I., Patrick, Kristin L., Watson, Robert O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8443056/
https://www.ncbi.nlm.nih.gov/pubmed/34473814
http://dx.doi.org/10.1371/journal.ppat.1009888

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8443056/
https://www.ncbi.nlm.nih.gov/pubmed/34473814
http://dx.doi.org/10.1371/journal.ppat.1009888

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