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The opportunistic intracellular bacterial pathogen Rhodococcus equi elicits type I interferon by engaging cytosolic DNA sensing in macrophages
Rhodococcus equi is a major cause of foal pneumonia and an opportunistic pathogen in immunocompromised humans. While alveolar macrophages constitute the primary replicative niche for R. equi, little is known about how intracellular R. equi is sensed by macrophages. Here, we discovered that in additi...
Autores principales: | Vail, Krystal J., da Silveira, Bibiana Petri, Bell, Samantha L., Cohen, Noah D., Bordin, Angela I., Patrick, Kristin L., Watson, Robert O. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8443056/ https://www.ncbi.nlm.nih.gov/pubmed/34473814 http://dx.doi.org/10.1371/journal.ppat.1009888 |
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