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Differential contribution to gene expression prediction of histone modifications at enhancers or promoters
The ChIP-seq signal of histone modifications at promoters is a good predictor of gene expression in different cellular contexts, but whether this is also true at enhancers is not clear. To address this issue, we develop quantitative models to characterize the relationship of gene expression with his...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8443064/ https://www.ncbi.nlm.nih.gov/pubmed/34473698 http://dx.doi.org/10.1371/journal.pcbi.1009368 |