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Nanoscale molecular architecture controls calcium diffusion and ER replenishment in dendritic spines

Dendritic spines are critical components of neuronal synapses as they receive and transform synaptic inputs into a succession of calcium-regulated biochemical events. The spine apparatus (SA), an extension of smooth endoplasmic reticulum, regulates slow and fast calcium dynamics in spines. Calcium r...

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Detalles Bibliográficos
Autores principales: Basnayake, Kanishka, Mazaud, David, Kushnireva, Lilia, Bemelmans, Alexis, Rouach, Nathalie, Korkotian, Eduard, Holcman, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8443180/
https://www.ncbi.nlm.nih.gov/pubmed/34524854
http://dx.doi.org/10.1126/sciadv.abh1376