Parallel characterization of cis-regulatory elements for multiple genes using CRISPRpath

Current pooled CRISPR screens for cis-regulatory elements (CREs), based on transcriptional output changes, are typically limited to characterizing CREs of only one gene. Here, we describe CRISPRpath, a scalable screening strategy for parallelly characterizing CREs of genes linked to the same biologi...

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Detalles Bibliográficos
Autores principales: Ren, Xingjie, Wang, Mengchi, Li, Bingkun, Jamieson, Kirsty, Zheng, Lina, Jones, Ian R., Li, Bin, Takagi, Maya Asami, Lee, Jerry, Maliskova, Lenka, Tam, Tsz Wai, Yu, Miao, Hu, Rong, Lee, Lindsay, Abnousi, Armen, Li, Gang, Li, Yun, Hu, Ming, Ren, Bing, Wang, Wei, Shen, Yin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8443183/
https://www.ncbi.nlm.nih.gov/pubmed/34524848
http://dx.doi.org/10.1126/sciadv.abi4360

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8443183/
https://www.ncbi.nlm.nih.gov/pubmed/34524848
http://dx.doi.org/10.1126/sciadv.abi4360

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