MYO10 drives genomic instability and inflammation in cancer

Genomic instability is a hallmark of human cancer; yet the underlying mechanisms remain poorly understood. Here, we report that the cytoplasmic unconventional Myosin X (MYO10) regulates genome stability, through which it mediates inflammation in cancer. MYO10 is an unstable protein that undergoes ub...

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Detalles Bibliográficos
Autores principales: Mayca Pozo, Franklin, Geng, Xinran, Tamagno, Ilaria, Jackson, Mark W., Heimsath, Ernest G., Hammer, John A., Cheney, Richard E., Zhang, Youwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8443186/
https://www.ncbi.nlm.nih.gov/pubmed/34524844
http://dx.doi.org/10.1126/sciadv.abg6908

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8443186/
https://www.ncbi.nlm.nih.gov/pubmed/34524844
http://dx.doi.org/10.1126/sciadv.abg6908

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