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MYO10 drives genomic instability and inflammation in cancer
Genomic instability is a hallmark of human cancer; yet the underlying mechanisms remain poorly understood. Here, we report that the cytoplasmic unconventional Myosin X (MYO10) regulates genome stability, through which it mediates inflammation in cancer. MYO10 is an unstable protein that undergoes ub...
Autores principales: | Mayca Pozo, Franklin, Geng, Xinran, Tamagno, Ilaria, Jackson, Mark W., Heimsath, Ernest G., Hammer, John A., Cheney, Richard E., Zhang, Youwei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8443186/ https://www.ncbi.nlm.nih.gov/pubmed/34524844 http://dx.doi.org/10.1126/sciadv.abg6908 |
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