TIPE2 is a checkpoint of natural killer cell maturation and antitumor immunity

The maturation process of NK cells determines their functionality during which IL-15 plays a critical role. However, very few checkpoints specifically targeting this process have been discovered. Here, we report that TIPE2 expression gradually increased during NK cell ontogenesis correlating to thei...

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Detalles Bibliográficos
Autores principales: Bi, Jiacheng, Cheng, Chen, Zheng, Chaoyue, Huang, Chen, Zheng, Xiaohu, Wan, Xiaochun, Chen, Youhai H., Tian, Zhigang, Sun, Haoyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8443187/
https://www.ncbi.nlm.nih.gov/pubmed/34524845
http://dx.doi.org/10.1126/sciadv.abi6515

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8443187/
https://www.ncbi.nlm.nih.gov/pubmed/34524845
http://dx.doi.org/10.1126/sciadv.abi6515

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