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TIPE2 is a checkpoint of natural killer cell maturation and antitumor immunity
The maturation process of NK cells determines their functionality during which IL-15 plays a critical role. However, very few checkpoints specifically targeting this process have been discovered. Here, we report that TIPE2 expression gradually increased during NK cell ontogenesis correlating to thei...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Association for the Advancement of Science
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8443187/ https://www.ncbi.nlm.nih.gov/pubmed/34524845 http://dx.doi.org/10.1126/sciadv.abi6515 |