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SUV39 SET domains mediate crosstalk of heterochromatic histone marks

The SUV39 class of methyltransferase enzymes deposits histone H3 lysine 9 di- and trimethylation (H3K9me2/3), the hallmark of constitutive heterochromatin. How these enzymes are regulated to mark specific genomic regions as heterochromatic is poorly understood. Clr4 is the sole H3K9me2/3 methyltrans...

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Detalles Bibliográficos
Autores principales: Stirpe, Alessandro, Guidotti, Nora, Northall, Sarah J, Kilic, Sinan, Hainard, Alexandre, Vadas, Oscar, Fierz, Beat, Schalch, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8443253/
https://www.ncbi.nlm.nih.gov/pubmed/34524082
http://dx.doi.org/10.7554/eLife.62682