RecA finds homologous DNA by reduced dimensionality search

Homologous recombination is essential for the accurate repair of double-stranded DNA breaks (DSBs)(1). Initially, the RecBCD complex(2) resects the ends of the DSB into 3′ single-stranded DNA on which a RecA filament assembles(3). Next, the filament locates the homologous repair template on the sist...

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Detalles Bibliográficos
Autores principales: Wiktor, Jakub, Gynnå, Arvid H., Leroy, Prune, Larsson, Jimmy, Coceano, Giovanna, Testa, Ilaria, Elf, Johan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8443446/
https://www.ncbi.nlm.nih.gov/pubmed/34471288
http://dx.doi.org/10.1038/s41586-021-03877-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8443446/
https://www.ncbi.nlm.nih.gov/pubmed/34471288
http://dx.doi.org/10.1038/s41586-021-03877-6

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