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RecA finds homologous DNA by reduced dimensionality search
Homologous recombination is essential for the accurate repair of double-stranded DNA breaks (DSBs)(1). Initially, the RecBCD complex(2) resects the ends of the DSB into 3′ single-stranded DNA on which a RecA filament assembles(3). Next, the filament locates the homologous repair template on the sist...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8443446/ https://www.ncbi.nlm.nih.gov/pubmed/34471288 http://dx.doi.org/10.1038/s41586-021-03877-6 |