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Mesenchymal stromal cells as carriers of IL-12 reduce primary and metastatic tumors of murine melanoma

Due to immunosuppressive properties and confirmed tropism towards cancer cells mesenchymal stromal cells (MSC) have been used in many trials. In our study we used these cells as carriers of IL-12 in the treatment of mice with primary and metastatic B16-F10 melanomas. IL-12 has confirmed anti-cancer...

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Detalles Bibliográficos
Autores principales: Kułach, Natalia, Pilny, Ewelina, Cichoń, Tomasz, Czapla, Justyna, Jarosz-Biej, Magdalena, Rusin, Marek, Drzyzga, Alina, Matuszczak, Sybilla, Szala, Stanisław, Smolarczyk, Ryszard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8443548/
https://www.ncbi.nlm.nih.gov/pubmed/34526531
http://dx.doi.org/10.1038/s41598-021-97435-9