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Functional and molecular characterization of a non-human primate model of autism spectrum disorder shows similarity with the human disease

Autism spectrum disorder (ASD) is a multifactorial disorder with characteristic synaptic and gene expression changes. Early intervention during childhood is thought to benefit prognosis. Here, we examined the changes in cortical synaptogenesis, synaptic function, and gene expression from birth to th...

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Detalles Bibliográficos
Autores principales: Watanabe, Satoshi, Kurotani, Tohru, Oga, Tomofumi, Noguchi, Jun, Isoda, Risa, Nakagami, Akiko, Sakai, Kazuhisa, Nakagaki, Keiko, Sumida, Kayo, Hoshino, Kohei, Saito, Koichi, Miyawaki, Izuru, Sekiguchi, Masayuki, Wada, Keiji, Minamimoto, Takafumi, Ichinohe, Noritaka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8443557/
https://www.ncbi.nlm.nih.gov/pubmed/34526497
http://dx.doi.org/10.1038/s41467-021-25487-6