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Glycyrrhizin ameliorating sterile inflammation induced by low-dose radiation exposure

Glycyrrhizin (GL) is a direct inhibitor of HMGB1 which acts as an alarmin when excreted into the extracellular space. High-dose radiation in radiotherapy induces collateral damage to the normal tissue, which can be mitigated by GL inhibiting HMGB1. The purpose of this study was to assess changes in...

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Detalles Bibliográficos
Autores principales: Kim, Hyung Cheol, Oh, Hyewon, You, Je Sung, Chung, Yong Eun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8443578/
https://www.ncbi.nlm.nih.gov/pubmed/34526618
http://dx.doi.org/10.1038/s41598-021-97800-8