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Modelling human liver fibrosis in the context of non-alcoholic steatohepatitis using a microphysiological system

Non-alcoholic steatohepatitis (NASH) is a common form of chronic liver disease characterised by lipid accumulation, infiltration of immune cells, hepatocellular ballooning, collagen deposition and liver fibrosis. There is a high unmet need to develop treatments for NASH. We have investigated how liv...

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Detalles Bibliográficos
Autores principales: Kostrzewski, Tomasz, Snow, Sophie, Battle, Anya Lindström, Peel, Samantha, Ahmad, Zahida, Basak, Jayati, Surakala, Manasa, Bornot, Aurelie, Lindgren, Julia, Ryaboshapkina, Maria, Clausen, Maryam, Lindén, Daniel, Maass, Christian, Young, Lucy May, Corrigan, Adam, Ewart, Lorna, Hughes, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8443589/
https://www.ncbi.nlm.nih.gov/pubmed/34526653
http://dx.doi.org/10.1038/s42003-021-02616-x