Integrative pan-cancer analysis of MEK1 aberrations and the potential clinical implications

Alterations of mitogen-activated protein kinase kinase 1 (MEK1) are commonly associated with tumorigenesis, and MEK1 is thought to be a suitable targeted therapy for various cancers. However, abnormal MEK1 alterations and their relevant clinical implications are unknown. Our research comprehensively...

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Detalles Bibliográficos
Autores principales: Zhou, Zhiyang, Peng, Bi, Li, Juanni, Gao, Kewa, Cai, Yuan, Xu, Zhijie, Yan, Yuanliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8443600/
https://www.ncbi.nlm.nih.gov/pubmed/34526571
http://dx.doi.org/10.1038/s41598-021-97840-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8443600/
https://www.ncbi.nlm.nih.gov/pubmed/34526571
http://dx.doi.org/10.1038/s41598-021-97840-0

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