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Integrative pan-cancer analysis of MEK1 aberrations and the potential clinical implications

Alterations of mitogen-activated protein kinase kinase 1 (MEK1) are commonly associated with tumorigenesis, and MEK1 is thought to be a suitable targeted therapy for various cancers. However, abnormal MEK1 alterations and their relevant clinical implications are unknown. Our research comprehensively...

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Detalles Bibliográficos
Autores principales:	Zhou, Zhiyang, Peng, Bi, Li, Juanni, Gao, Kewa, Cai, Yuan, Xu, Zhijie, Yan, Yuanliang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8443600/ https://www.ncbi.nlm.nih.gov/pubmed/34526571 http://dx.doi.org/10.1038/s41598-021-97840-0

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