Nrf2 activation does not affect adenoma development in a mouse model of colorectal cancer

Transcription factor nuclear factor erythroid 2 p45-related factor 2 (Nrf2) and its main negative regulator, Kelch-like ECH associated protein 1 (Keap1), are at the interface between redox and intermediary metabolism. Nrf2 activation is protective in models of human disease and has benefits in clini...

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Detalles Bibliográficos
Autores principales: Knatko, Elena V., Castro, Cecilia, Higgins, Maureen, Zhang, Ying, Honda, Tadashi, Henderson, Colin J., Wolf, C. Roland, Griffin, Julian L., Dinkova-Kostova, Albena T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8443638/
https://www.ncbi.nlm.nih.gov/pubmed/34526660
http://dx.doi.org/10.1038/s42003-021-02552-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8443638/
https://www.ncbi.nlm.nih.gov/pubmed/34526660
http://dx.doi.org/10.1038/s42003-021-02552-w

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