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Empagliflozin maintains capillarization and improves cardiac function in a murine model of left ventricular pressure overload

Patients with type 2 diabetes treated with Sodium glucose transporter 2 (SGLT2) inhibitors show reduced mortality and hospitalization for heart failure (HF). SGLT2 inhibitors are considered to activate multiple cardioprotective pathways; however, underlying mechanisms are not fully described. This s...

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Detalles Bibliográficos
Autores principales: Nakao, Masaaki, Shimizu, Ippei, Katsuumi, Goro, Yoshida, Yohko, Suda, Masayoshi, Hayashi, Yuka, Ikegami, Ryutaro, Hsiao, Yung Ting, Okuda, Shujiro, Soga, Tomoyoshi, Minamino, Tohru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8443662/
https://www.ncbi.nlm.nih.gov/pubmed/34526601
http://dx.doi.org/10.1038/s41598-021-97787-2