Structural determinants and regulation of spontaneous activity in GABA(A) receptors

GABA(A) receptors are vital for controlling neuronal excitability and can display significant levels of constitutive activity that contributes to tonic inhibition. However, the mechanisms underlying spontaneity are poorly understood. Here we demonstrate a strict requirement for β3 subunit incorporat...

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Detalles Bibliográficos
Autores principales: Sexton, Craig A., Penzinger, Reka, Mortensen, Martin, Bright, Damian P., Smart, Trevor G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8443696/
https://www.ncbi.nlm.nih.gov/pubmed/34526505
http://dx.doi.org/10.1038/s41467-021-25633-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8443696/
https://www.ncbi.nlm.nih.gov/pubmed/34526505
http://dx.doi.org/10.1038/s41467-021-25633-0

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